{"id":56161,"date":"2018-10-05T10:23:54","date_gmt":"2018-10-05T08:23:54","guid":{"rendered":"https:\/\/biovet-alquermes.com\/biovet-s-a-gives-a-conference-in-ukraine-on-a-trial-with-a-natural-preservative\/"},"modified":"2024-04-22T12:10:20","modified_gmt":"2024-04-22T10:10:20","slug":"biovet-s-a-gives-a-conference-in-ukraine-on-a-trial-with-a-natural-preservative","status":"publish","type":"post","link":"https:\/\/biovet-alquermes.com\/en\/2018\/10\/05\/biovet-s-a-gives-a-conference-in-ukraine-on-a-trial-with-a-natural-preservative\/","title":{"rendered":"Biovet S.A gives a conference in Ukraine on a trial with a natural preservative"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-8823 size-full\" src=\"https:\/\/biovet-alquermes.com\/wp-content\/uploads\/2024\/04\/5119438e68bce0412cd5cb6dd9e37e4bfd69822f-1-2.jpg\" alt=\"\" width=\"900\" height=\"600\" \/><\/p>\n<p><strong>Dr. Veniamin Osypov, a nutritionist and Biovet S.A technical consultant in the Eastern Europe,<\/strong>\u00a0gave a lecture in Truskavets (Ukraine), at the beginning of September, on a trial on broilers that evaluated the use of Alquermold Natural (a natural preservative with cimenol ring) as prevention and treatment for necrotic enteritis, caused by\u00a0<em>Clostridium perfringens<\/em>. I<em>n vivo<\/em>\u00a0research was carried out at the Scientific University of the South (\u201c<strong>Universidad Cient\u00edfica<\/strong>\u201d) (<strong>Peru<\/strong>) in September 2017. The bactericidal effects of the product on the productive parameters in broilers challenged with\u00a0<em>Clostridium perfringens<\/em>\u00a0(artificial infection) were analyzed.<\/p>\n<p><strong><a href=\"https:\/\/biovet-alquermes.com\/en\/producto\/alquermold-natural-p-and-l\/\" target=\"_blank\" rel=\"No follow noopener\">Alquermold Natural\u00a0<\/a>controls the pathogenic intestinal flora and functions as a preservative of raw materials and feed.<\/strong>\u00a0It is a natural product developed by Biovet S.A Laboratories,\u00a0<strong>composed of ring cimenol and citric acid.<\/strong><\/p>\n<p>The trial was performed with a total of 504 Cobb 500 broilers, distributed in 4 treatments (126 animals \/ batch). Animals were divided into 4 batches.<strong>\u00a0T-1 or Negative Control &#8211;<\/strong>fed standard basal diet and without\u00a0<em>Clostridium perfringens<\/em>\u00a0challenge-, while the other 3 batches were challenged:\u00a0<strong>T-2 or Positive Control &#8211;<\/strong>standard basal diet + challenge with\u00a0<em>Clostridium perfringens-<\/em>;\u00a0<strong>T-3 or natural preservative (solid) with cimenol ring as a preventive treatment<\/strong>\u00a0and finally,\u00a0<strong>T-4 or natural preservative (liquid) with cimenol ring<\/strong>\u00a0as therapeutic\u00a0<strong>treatment<\/strong>. In this latter case, administration of the preservative started when the symptoms of the disease appeared.<\/p>\n<p><strong>NATURAL PRESERVATIVE AS PREVENTIVE TREATMENT<\/strong><\/p>\n<p>Regarding the\u00a0<strong>productive parameters<\/strong>\u00a0(weight, conversion rate, uniformity, carcass yield and mortality),\u00a0<strong>broilers in T-3 batch (cimenol ring as a preventive) obtained significantly better results, compared to T-2 batch.<\/strong><\/p>\n<p>When evaluating carcass yield, poultry in\u00a0<strong>T-3 batch had the highest carcass yield and the lowest abdominal fat percentage.\u00a0<\/strong>In the case of the\u00a0<strong>microbiological analyzes<\/strong>\u00a0(Sulphite-reducting\u00a0<em>Clostridium)<\/em>\u00a0T-3 batch (cimenol ring as preventive) had the lowest post -infection CFU (Colony Forming Units) count in duodenum and cecum post-infection.<\/p>\n<p><strong>Histopathology<\/strong>\u00a0confirmed that T-2 batch (infected non-treated) was the batch with more animals with necrotic enteritis lesions, and these were more severe than in other batches, showing atrophy, necrosis and ulcers.\u00a0<strong>T-3 batch was the one with the lowest number of lesions and these were the mildest<\/strong>.<\/p>\n<p>Lastly, the study evaluated the\u00a0<strong>intestinal morphometry<\/strong>, which showed that the mucosal length was the shortest in T-2 (infected),\u00a0<strong>and that broilers in T-3 (preservative as preventive) showed the longest mucosal length, which was even longer than the mucosa of the control batch (T-1).<\/strong><\/p>\n<p><strong>NATURAL PRESERVATIVE AS TREATMENT<\/strong><\/p>\n<p>On the other hand, after\u00a0<em>Clostridium perfringens challenge<\/em>, T-4 broilers (cimenol ring as treatment), which received\u00a0<strong>Alquermold Natural administered in the drinking water, improved their weight gain\/birth\/day, feed conversion rate and uniformity<\/strong>, compared to T-2 (infected and non-treated). In regard to\u00a0<strong>mortality<\/strong>\u00a0in this batch, results showed that it was lower than in T-2 (infected non-treated).<\/p>\n<p>When evaluating carcass yield,<strong>\u00a0T-4\u00a0partly recovered it after infection<\/strong>, but it did not reach normal values.<\/p>\n<p>In the case of\u00a0<strong>microbiological analyzes<\/strong>\u00a0(Sulphite-reducting\u00a0<em>Clostridium<\/em>), treatment with cimenol ring (T-4) reduced the CFU count in duodenum and cecum compared with T-2 batch (infected non-treated).<\/p>\n<p>Regarding\u00a0<strong>histopathology,<\/strong>\u00a0T-4 batch had less lesions than T-2, and these lesions were milder than T2 batch (infected non-treated).<\/p>\n<p><strong>RECOMMENDATIONS<\/strong><\/p>\n<p>Finally, the nutritionist made some recommendations in which he emphasized that:\u00a0<strong>&#8220;this natural preservative with cimenol ring\u00a0<\/strong>can be used in both situations: to prevent necrotic enteritis in broilers and as treatment against an outbreak of necrotic enteritis\u201d.<\/p>\n<p>You can see the charts of this research in our Technonews blog:<\/p>\n<p><a href=\"http:\/\/www.veterinariadigital.com\/uk\/blogs\/technonews\/effect-of-cimenol-ring-in-broilers-challenged-with-clostridium-perfringens\">http:\/\/www.veterinariadigital.com\/uk\/blogs\/technonews\/effect-of-cimenol-ring-in-broilers-challenged-with-clostridium-perfringens<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Veniamin Osypov, a nutritionist and Biovet S.A technical consultant in the Eastern Europe,\u00a0gave a lecture in Truskavets (Ukraine), at the beginning of September, on a trial on broilers that evaluated the use of Alquermold Natural  as prevention and treatment for necrotic enteritis, caused by\u00a0Clostridium perfringens<\/p>\n","protected":false},"author":1,"featured_media":33135,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1555,1918],"tags":[],"class_list":["post-56161","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-poultry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - 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