{"id":55016,"date":"2018-02-13T07:31:55","date_gmt":"2018-02-13T06:31:55","guid":{"rendered":"https:\/\/biovet-alquermes.com\/use-of-intestinal-conditioner-pronutrients-to-improve-the-absorption-of-the-vitamin-from-the-diet\/"},"modified":"2024-04-22T12:02:21","modified_gmt":"2024-04-22T10:02:21","slug":"use-of-intestinal-conditioner-pronutrients-to-improve-the-absorption-of-the-vitamin-from-the-diet","status":"publish","type":"post","link":"https:\/\/biovet-alquermes.com\/en\/2018\/02\/13\/use-of-intestinal-conditioner-pronutrients-to-improve-the-absorption-of-the-vitamin-from-the-diet\/","title":{"rendered":"Use of intestinal conditioner pronutrients to improve the absorption of the vitamin from the diet."},"content":{"rendered":"<p><img decoding=\"async\" src=\"https:\/\/biovet-alquermes.com\/wp-content\/uploads\/2024\/04\/PodiumNebsui.png\" \/><\/p>\n<p><i><span lang=\"EN-US\">In vitro<\/span><\/i><span lang=\"EN-US\">\u00a0trial carried out in 2018 with vitamins B12, B1, E, A and D3.<\/span><\/p>\n<p><b><strong>Introduction:<\/strong><\/b><\/p>\n<p>In an\u00a0<em>in vitro<\/em>\u00a0trial carried out in January 2018,\u00a0<b><strong>the ability to promote the absorption of different vitamins<\/strong><\/b>\u00a0<b><strong>included in the diet<\/strong><\/b>\u00a0of a product based on pronutrients that act as conditioners of the intestinal mucosa was analyzed.<\/p>\n<p><b><strong>Material and methods:<\/strong><\/b><\/p>\n<p>The assay was performed in nine 6-well plates where 1.2\u00d710<sup>5<\/sup>\u00a0cells\/ml were added in a 3ml volume per well.<\/p>\n<p>After four days of growth, confluence was reached and culture medium was substituted and supplemented with Alquernat Nebsui (1:10.000 and 1:5000) in six plates, while other three were used as untreated negative controls.<\/p>\n<p>After 60 minutes of exposure to intestinal conditioner, medium was removed and HBSS medium (3 wells\/plate) or HBSS supplemented with Vitamin B1, B12, A, E or D3, 5 microM (3 wells\/plate) was added.<\/p>\n<p>After 90 minutes, cells were washed, lysed and intracellular concentration of vitamin was measured by a colorimetric assay method.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biovet-alquermes.com\/wp-content\/uploads\/2024\/04\/grafic1.png\" \/><\/p>\n<p style=\"font-weight: 200;\"><b><strong>Results:<\/strong><\/b><\/p>\n<p style=\"font-weight: 200;\"><b><strong>Intestinal conditioner pronutrients increase the exogenous absorption of water and fat-soluble vitamins in the intestinal epithelial cells:<\/strong><\/b><\/p>\n<p style=\"font-weight: 200;\"><b><strong>Vitamin B12<\/strong><\/b><\/p>\n<p style=\"font-weight: 200;\">As shown in the graphs, there was a 30% increase in the exogenous absorption of Vitamin B12.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biovet-alquermes.com\/wp-content\/uploads\/2024\/04\/1.png\" \/><\/p>\n<p><b><span lang=\"EN-US\">Vitamin B1<\/span><\/b><\/p>\n<p>Likewise, there was a 56% increase in the exogenous absorption of vitamin B1.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biovet-alquermes.com\/wp-content\/uploads\/2024\/04\/2.png\" \/><\/p>\n<p><b><span lang=\"EN-US\">Vitamina E<\/span><\/b><\/p>\n<p>The exogenous absorption of vitamin E was also increased by 39%.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biovet-alquermes.com\/wp-content\/uploads\/2024\/04\/3.png\" \/><\/p>\n<p><b><span lang=\"EN-US\">Vitamin A<\/span><\/b><\/p>\n<p>The exogenous absorption of vitamin A was 43%.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biovet-alquermes.com\/wp-content\/uploads\/2024\/04\/4.png\" \/><\/p>\n<p style=\"font-weight: 200;\"><b><strong>Vitamin D3<\/strong><\/b><\/p>\n<p style=\"font-weight: 200;\">In addition, the exogenous absorption of vitamin D3 was increased by 15%.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biovet-alquermes.com\/wp-content\/uploads\/2024\/04\/Nebsui1.png\" \/><\/p>\n<p style=\"font-weight: 200;\"><b><strong>Conclusions:<\/strong><\/b><\/p>\n<p style=\"font-weight: 200;\"><b><strong>Intestinal conditioner pronutrients allow lower inclusion rates of these water and fat-soluble vitamins in animal feed (vitamin B1, B12, A, E and D3), with the consequent cost reduction.\u00a0<\/strong><\/b>It is an important factor considering the high costs of vitamins in the current market.<\/p>\n<table style=\"font-weight: 200;\">\n<tbody>\n<tr>\n<td width=\"141\">\n<p style=\"text-align: center;\"><b><strong>Vitamin B12<\/strong><\/b><\/p>\n<\/td>\n<td style=\"text-align: center;\" width=\"95\"><b><strong>+30%<\/strong><\/b><\/td>\n<\/tr>\n<tr>\n<td width=\"141\">\n<p style=\"text-align: center;\"><b><strong>Vitamin B1<\/strong><\/b><\/p>\n<\/td>\n<td width=\"95\">\n<p style=\"text-align: center;\"><b><strong>+56%<\/strong><\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"141\">\n<p style=\"text-align: center;\"><b><strong>Vitamin E<\/strong><\/b><\/p>\n<\/td>\n<td width=\"95\">\n<p style=\"text-align: center;\"><b><strong>+39%<\/strong><\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" width=\"141\"><b><strong>Vitamin A<\/strong><\/b><\/td>\n<td width=\"95\">\n<p style=\"text-align: center;\"><b><strong>+43%<\/strong><\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" width=\"141\"><b><strong>Vitamin D3<\/strong><\/b><\/td>\n<td width=\"95\">\n<p style=\"text-align: center;\"><b><strong>+15%<\/strong><\/b><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"font-weight: 200;\">\nAfter years of research, the company specializing in the manufacture of additives,\u00a0<b><strong>Biovet S.A.,<\/strong><\/b>\u00a0<b><strong>has selected intestinal conditioners<\/strong><\/b>\u00a0that optimize the structure of the intestinal mucosa and stimulate the regeneration of the intestinal cells, increasing their functionality and efficiency.<\/p>\n<p style=\"font-weight: 200;\">In such a way that they improve the physiological state of the intestinal mucosa, increasing the absorption of both water and fat-soluble vitamins, as well as controlling the growth of intestinal pathogens and improving the absorption of the nutrients in the diet.<\/p>\n<p><b><span lang=\"EN\">Intestinal conditioner pronutrients are commercialized as the product ALQUERNAT NEBSUI, of Biovet S.A.<\/span><\/b><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In vitro\u00a0trial carried out in 2018 with vitamins B12, B1, E, A and D3. Introduction: In an\u00a0in vitro\u00a0trial carried out in January 2018,\u00a0the ability to promote the absorption of different vitamins\u00a0included in the diet\u00a0of a product based on pronutrients that act as conditioners of the intestinal mucosa was analyzed. Material and methods: The assay was [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":31155,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1555],"tags":[],"class_list":["post-55016","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Use of intestinal conditioner pronutrients to improve the absorption of the vitamin from the diet. - Biovet<\/title>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Use of intestinal conditioner pronutrients to improve the absorption of the vitamin from the diet. - Biovet\" \/>\n<meta property=\"og:description\" content=\"In vitro\u00a0trial carried out in 2018 with vitamins B12, B1, E, A and D3. Introduction: In an\u00a0in vitro\u00a0trial carried out in January 2018,\u00a0the ability to promote the absorption of different vitamins\u00a0included in the diet\u00a0of a product based on pronutrients that act as conditioners of the intestinal mucosa was analyzed. 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Introduction: In an\u00a0in vitro\u00a0trial carried out in January 2018,\u00a0the ability to promote the absorption of different vitamins\u00a0included in the diet\u00a0of a product based on pronutrients that act as conditioners of the intestinal mucosa was analyzed. 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